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Interpreting Patterns of Gene Expression: Signatures of Coregulation, the Data Processing Inequality, and Triplet Motifs

Various methods of reconstructing transcriptional regulatory networks infer transcriptional regulatory interactions (TRIs) between strongly coexpressed gene pairs (as determined from microarray experiments measuring mRNA levels). Alternatively, however, the coexpression of two genes might imply that...

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Detalles Bibliográficos
Autores principales: Ku, Wai Lim, Duggal, Geet, Li, Yuan, Girvan, Michelle, Ott, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290541/
https://www.ncbi.nlm.nih.gov/pubmed/22393375
http://dx.doi.org/10.1371/journal.pone.0031969