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Myelin 2′,3′-Cyclic Nucleotide 3′-Phosphodiesterase: Active-Site Ligand Binding and Molecular Conformation

The 2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase) is a highly abundant membrane-associated enzyme in the myelin sheath of the vertebrate nervous system. CNPase is a member of the 2H phosphoesterase family and catalyzes the formation of 2′-nucleotide products from 2′,3′-cyclic substrates; how...

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Detalles Bibliográficos
Autores principales: Myllykoski, Matti, Raasakka, Arne, Han, Huijong, Kursula, Petri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290555/
https://www.ncbi.nlm.nih.gov/pubmed/22393399
http://dx.doi.org/10.1371/journal.pone.0032336