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IL-10 Regulates Viral Lung Immunopathology during Acute Respiratory Syncytial Virus Infection in Mice

Interleukin (IL-) 10 is a pleiotropic cytokine with broad immunosuppressive functions, particularly at mucosal sites such as the intestine and lung. Here we demonstrate that infection of BALB/c mice with respiratory syncytial virus (RSV) induced IL-10 production by CD4(+) and CD8(+) T cells in the a...

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Detalles Bibliográficos
Autores principales: Loebbermann, Jens, Schnoeller, Corinna, Thornton, Hannah, Durant, Lydia, Sweeney, Nathan P., Schuijs, Martijn, O'Garra, Anne, Johansson, Cecilia, Openshaw, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290561/
https://www.ncbi.nlm.nih.gov/pubmed/22393401
http://dx.doi.org/10.1371/journal.pone.0032371