The Nitric Oxide-Cyclic GMP Pathway Regulates FoxO and Alters Dopaminergic Neuron Survival in Drosophila

Activation of the forkhead box transcription factor FoxO is suggested to be involved in dopaminergic (DA) neurodegeneration in a Drosophila model of Parkinson's disease (PD), in which a PD gene product LRRK2 activates FoxO through phosphorylation. In the current study that combines Drosophila g...

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Detalles Bibliográficos
Autores principales: Kanao, Tomoko, Sawada, Tomoyo, Davies, Shireen-Anne, Ichinose, Hiroshi, Hasegawa, Kazuko, Takahashi, Ryosuke, Hattori, Nobutaka, Imai, Yuzuru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290610/
https://www.ncbi.nlm.nih.gov/pubmed/22393355
http://dx.doi.org/10.1371/journal.pone.0030958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290610/
https://www.ncbi.nlm.nih.gov/pubmed/22393355
http://dx.doi.org/10.1371/journal.pone.0030958

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