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The Nitric Oxide-Cyclic GMP Pathway Regulates FoxO and Alters Dopaminergic Neuron Survival in Drosophila
Activation of the forkhead box transcription factor FoxO is suggested to be involved in dopaminergic (DA) neurodegeneration in a Drosophila model of Parkinson's disease (PD), in which a PD gene product LRRK2 activates FoxO through phosphorylation. In the current study that combines Drosophila g...
Autores principales: | Kanao, Tomoko, Sawada, Tomoyo, Davies, Shireen-Anne, Ichinose, Hiroshi, Hasegawa, Kazuko, Takahashi, Ryosuke, Hattori, Nobutaka, Imai, Yuzuru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290610/ https://www.ncbi.nlm.nih.gov/pubmed/22393355 http://dx.doi.org/10.1371/journal.pone.0030958 |
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