Decrease of miR-146b-5p in Monocytes during Obesity Is Associated with Loss of the Anti-Inflammatory but Not Insulin Signaling Action of Adiponectin

BACKGROUND: Low adiponectin, a well-recognized antidiabetic adipokine, has been associated with obesity-related inflammation, oxidative stress and insulin resistance. Globular adiponectin is an important regulator of the interleukin-1 receptor-associated kinase (IRAK)/NFκB pathway in monocytes of ob...

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Detalles Bibliográficos
Autores principales: Hulsmans, Maarten, Van Dooren, Els, Mathieu, Chantal, Holvoet, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290617/
https://www.ncbi.nlm.nih.gov/pubmed/22393448
http://dx.doi.org/10.1371/journal.pone.0032794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290617/
https://www.ncbi.nlm.nih.gov/pubmed/22393448
http://dx.doi.org/10.1371/journal.pone.0032794

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