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Differential Differences in Methylation Status of Putative Imprinted Genes among Cloned Swine Genomes
DNA methylation is a major epigenetic modification in the mammalian genome that regulates crucial aspects of gene function. Mammalian cloning by somatic cell nuclear transfer (SCNT) often results in gestational or neonatal failure with only a small proportion of manipulated embryos producing live bi...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290620/ https://www.ncbi.nlm.nih.gov/pubmed/22393450 http://dx.doi.org/10.1371/journal.pone.0032812 |