Differential Differences in Methylation Status of Putative Imprinted Genes among Cloned Swine Genomes

DNA methylation is a major epigenetic modification in the mammalian genome that regulates crucial aspects of gene function. Mammalian cloning by somatic cell nuclear transfer (SCNT) often results in gestational or neonatal failure with only a small proportion of manipulated embryos producing live bi...

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Detalles Bibliográficos
Autores principales: Shen, Chih-Jie, Cheng, Winston T. K., Wu, Shinn-Chih, Chen, Hsiao-Ling, Tsai, Tung-Chou, Yang, Shang-Hsun, Chen, Chuan-Mu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290620/
https://www.ncbi.nlm.nih.gov/pubmed/22393450
http://dx.doi.org/10.1371/journal.pone.0032812

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