Discovery of Inhibitors of Leishmania β-1,2-Mannosyltransferases Using a Click-Chemistry-Derived Guanosine Monophosphate Library

Leishmania spp. are a medically important group of protozoan parasites that synthesize a novel intracellular carbohydrate reserve polymer termed mannogen. Mannogen is a soluble homopolymer of β-1,2-linked mannose residues that accumulates in the major pathogenic stages in the sandfly vector and mamm...

Descripción completa

Detalles Bibliográficos
Autores principales: van der Peet, Phillip, Ralton, Julie E., McConville, Malcolm J., Williams, Spencer J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290622/
https://www.ncbi.nlm.nih.gov/pubmed/22393429
http://dx.doi.org/10.1371/journal.pone.0032642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290622/
https://www.ncbi.nlm.nih.gov/pubmed/22393429
http://dx.doi.org/10.1371/journal.pone.0032642

Ejemplares similares