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Discovery of Inhibitors of Leishmania β-1,2-Mannosyltransferases Using a Click-Chemistry-Derived Guanosine Monophosphate Library

Leishmania spp. are a medically important group of protozoan parasites that synthesize a novel intracellular carbohydrate reserve polymer termed mannogen. Mannogen is a soluble homopolymer of β-1,2-linked mannose residues that accumulates in the major pathogenic stages in the sandfly vector and mamm...

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Detalles Bibliográficos
Autores principales:	van der Peet, Phillip, Ralton, Julie E., McConville, Malcolm J., Williams, Spencer J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290622/ https://www.ncbi.nlm.nih.gov/pubmed/22393429 http://dx.doi.org/10.1371/journal.pone.0032642

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