Enhanced Notch Activation Is Advantageous but Not Essential for T Cell Lymphomagenesis in Id1 Transgenic Mice

T cell lymphoblastic leukemia (T-ALL) is known to be associated with chromosomal abnormalities that lead to aberrant expression of a number of transcription factors such as TAL1, which dimerizes with basic helix-loop-helix (bHLH) E proteins and inhibits their function. Activated Notch receptors also...

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Detalles Bibliográficos
Autores principales: Wang, Hong-Cheng, Peng, Vincent, Zhao, Ying, Sun, Xiao-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290631/
https://www.ncbi.nlm.nih.gov/pubmed/22393458
http://dx.doi.org/10.1371/journal.pone.0032944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290631/
https://www.ncbi.nlm.nih.gov/pubmed/22393458
http://dx.doi.org/10.1371/journal.pone.0032944

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