Inhibition of fatty acid oxidation enhances oxidative protein folding and protects hepatocytes from endoplasmic reticulum stress

The unfolded protein response (UPR) signals protein misfolding in the endoplasmic reticulum (ER) to effect gene expression changes and restore ER homeostasis. Although many UPR-regulated genes encode ER protein processing factors, others, such as those encoding lipid catabolism enzymes, seem unrelat...

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Detalles Bibliográficos
Autores principales: Tyra, Heather M., Spitz, Douglas R., Rutkowski, D. Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290641/
https://www.ncbi.nlm.nih.gov/pubmed/22262455
http://dx.doi.org/10.1091/mbc.E11-12-1011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290641/
https://www.ncbi.nlm.nih.gov/pubmed/22262455
http://dx.doi.org/10.1091/mbc.E11-12-1011

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