Single-molecule imaging of translational output from individual RNA granules in neurons

Dendritic RNAs are localized and translated in RNA granules. Here we use single-molecule imaging to count the number of RNA molecules in each granule and to record translation output from each granule using Venus fluorescent protein as a reporter. For RNAs encoding activity-regulated cytoskeletal-as...

Descripción completa

Detalles Bibliográficos
Autores principales: Tatavarty, Vedakumar, Ifrim, Marius F., Levin, Mikhail, Korza, George, Barbarese, Elisa, Yu, Ji, Carson, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290649/
https://www.ncbi.nlm.nih.gov/pubmed/22219377
http://dx.doi.org/10.1091/mbc.E11-07-0622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290649/
https://www.ncbi.nlm.nih.gov/pubmed/22219377
http://dx.doi.org/10.1091/mbc.E11-07-0622

Ejemplares similares