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Single-molecule imaging of translational output from individual RNA granules in neurons
Dendritic RNAs are localized and translated in RNA granules. Here we use single-molecule imaging to count the number of RNA molecules in each granule and to record translation output from each granule using Venus fluorescent protein as a reporter. For RNAs encoding activity-regulated cytoskeletal-as...
Autores principales: | Tatavarty, Vedakumar, Ifrim, Marius F., Levin, Mikhail, Korza, George, Barbarese, Elisa, Yu, Ji, Carson, John H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290649/ https://www.ncbi.nlm.nih.gov/pubmed/22219377 http://dx.doi.org/10.1091/mbc.E11-07-0622 |
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