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Kar2p availability defines distinct forms of endoplasmic reticulum stress in living cells

Accumulation of misfolded secretory proteins in the endoplasmic reticulum (ER) activates the unfolded protein response (UPR) stress pathway. To enhance secretory protein folding and promote adaptation to stress, the UPR upregulates ER chaperone levels, including BiP. Here we describe chromosomal tag...

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Detalles Bibliográficos
Autores principales: Lajoie, Patrick, Moir, Robyn D., Willis, Ian M., Snapp, Erik L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290652/
https://www.ncbi.nlm.nih.gov/pubmed/22219379
http://dx.doi.org/10.1091/mbc.E11-12-0995