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Reduced cell proliferation by IKK2 depletion in a mouse lung cancer model
Lung cancer is one of the leading cancer malignancies with a five-year survival rate of only ~15%. We have developed a lentiviral vector mediated mouse model which allows generation of non-small cell lung cancer from less than one hundred alveolar epithelial cells, and investigated the role of IKK2...
Autores principales: | Xia, Yifeng, Yeddula, Narayana, Leblanc, Mathias, Ke, Eugene, Zhang, Yonghui, Oldfield, Eric, Shaw, Reuben J., Verma, Inder M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290728/ https://www.ncbi.nlm.nih.gov/pubmed/22327365 http://dx.doi.org/10.1038/ncb2428 |
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