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Reduced cell proliferation by IKK2 depletion in a mouse lung cancer model

Lung cancer is one of the leading cancer malignancies with a five-year survival rate of only ~15%. We have developed a lentiviral vector mediated mouse model which allows generation of non-small cell lung cancer from less than one hundred alveolar epithelial cells, and investigated the role of IKK2...

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Detalles Bibliográficos
Autores principales: Xia, Yifeng, Yeddula, Narayana, Leblanc, Mathias, Ke, Eugene, Zhang, Yonghui, Oldfield, Eric, Shaw, Reuben J., Verma, Inder M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290728/
https://www.ncbi.nlm.nih.gov/pubmed/22327365
http://dx.doi.org/10.1038/ncb2428