Structural Basis for the Activation of IKK1/α

Distinct signaling pathways activate the NF-κB family of transcription factors. The canonical NF-κB-signaling pathway is mediated by IκB kinase 2/β (IKK2/β), while the non-canonical pathway depends on IKK1/α. The structural and biochemical bases for distinct signaling by these otherwise highly simil...

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Detalles Bibliográficos
Autores principales: Polley, Smarajit, Passos, Dario Oliveira, Huang, De-Bin, Mulero, Maria Carmen, Mazumder, Anup, Biswas, Tapan, Verma, Inder M., Lyumkis, Dmitry, Ghosh, Gourisankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508515/
https://www.ncbi.nlm.nih.gov/pubmed/27851956
http://dx.doi.org/10.1016/j.celrep.2016.10.067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508515/
https://www.ncbi.nlm.nih.gov/pubmed/27851956
http://dx.doi.org/10.1016/j.celrep.2016.10.067

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