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Knockdown of IKKβ Inhibits Tumor Development in a Leptomeningeal Metastasis Mouse Model and Proliferation of Lung Cancer Cells

OBJECTIVE: This study will explore the role of IKKβ in the leptomeningeal metastasis (LM) of lung cancer cells. METHODS: In vitro studies were conducted in mouse Lewis lung carcinoma (LLC) cells with IKKβ knockdown. Cell proliferation was explored using CCK-8 and tumor colony-forming assays. The exp...

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Detalles Bibliográficos
Autores principales: Liu, Yakun, Li, Yuanyuan, Li, Zhongyao, Li, Chunyan, He, Junying, Bu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381159/
https://www.ncbi.nlm.nih.gov/pubmed/32765100
http://dx.doi.org/10.2147/CMAR.S252184