Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukemia

Tissue stromal cells interact with leukemia cells and profoundly affect their viability and drug sensitivity. Here we show a biochemical mechanism by which bone marrow stromal cells modulate the redox status of chronic lymphocytic leukemia (CLL) cells and promote cellular survival and drug resistanc...

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Detalles Bibliográficos
Autores principales: Zhang, Wan, Trachootham, Dunyaporn, Liu, Jinyun, Chen, Gang, Pelicano, Helene, Garcia-Prieto, Celia, Lu, Weiqin, Burger, Jan A, Croce, Carlo M, Plunkett, William, Keating, Michael J, Huang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290742/
https://www.ncbi.nlm.nih.gov/pubmed/22344033
http://dx.doi.org/10.1038/ncb2432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290742/
https://www.ncbi.nlm.nih.gov/pubmed/22344033
http://dx.doi.org/10.1038/ncb2432

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