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Revisiting inward rectification: K ions permeate through Kir2.1 channels during high-affinity block by spermidine
Outward currents through Kir2.1 channels play crucial roles in controlling the electrical properties of excitable cells, and such currents are subjected to voltage-dependent block by intracellular Mg(2+) and polyamines that bind to both high- and low-affinity sites on the channels. Under physiologic...
Autores principales: | Liu, Tai-An, Chang, Hsueh-Kai, Shieh, Ru-Chi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290795/ https://www.ncbi.nlm.nih.gov/pubmed/22371365 http://dx.doi.org/10.1085/jgp.201110736 |
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