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Toll-Like Receptors in Ischaemia and Its Potential Role in the Pathophysiology of Muscle Damage in Critical Limb Ischaemia

Toll-like receptors (TLRs) are key receptors of the innate immune system which are expressed on immune and nonimmune cells. They are activated by both pathogen-associated molecular patterns and endogenous ligands. Activation of TLRs culminates in the release of proinflammatory cytokines, chemokines,...

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Detalles Bibliográficos
Autores principales: Patel, Hemanshu, Shaw, Sidney G., Shi-Wen, Xu, Abraham, David, Baker, Daryll M., Tsui, Janice C. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290818/
https://www.ncbi.nlm.nih.gov/pubmed/22454775
http://dx.doi.org/10.1155/2012/121237