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CYBA Gene Polymorphisms and Adverse Outcomes in Acute Kidney Injury: A Prospective Cohort Study

BACKGROUND: NADPH oxidase is an important enzyme involved in the generation of reactive oxygen species in acute kidney injury (AKI). Its key subunit, p22(phox), is encoded by the highly polymorphic CYBA gene. METHODS: We examined the associations of CYBA gene polymorphisms across the CYBA locus (rs8...

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Detalles Bibliográficos
Autores principales: Perianayagam, Mary C., Tighiouart, Hocine, Nievergelt, Caroline M., O'Connor, Daniel T., Liangos, Orfeas, Jaber, Bertrand L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290849/
https://www.ncbi.nlm.nih.gov/pubmed/22470385
http://dx.doi.org/10.1159/000333017