Cargando…

Adeno-Associated Virus-Mediated Gene Transfer to Renal Tubule Cells via a Retrograde Ureteral Approach

BACKGROUND/AIMS: Gene therapy involves delivery of exogenous DNA to provide a therapeutic protein. Ideally, a gene therapy vector should be non-toxic, non-immunogenic, easy to produce, and efficient in protecting and delivering DNA into target cells. METHODS: Adeno-associated virus (AAV) offers thes...

Descripción completa

Detalles Bibliográficos
Autores principales: Chung, Daniel C., Fogelgren, Ben, Park, Kwon Moo, Heidenberg, Jessica, Zuo, Xiaofeng, Huang, Liwei, Bennett, Jean, Lipschutz, Joshua H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290852/
https://www.ncbi.nlm.nih.gov/pubmed/22470395
http://dx.doi.org/10.1159/000333071