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Adeno-Associated Virus-Mediated Gene Transfer to Renal Tubule Cells via a Retrograde Ureteral Approach

BACKGROUND/AIMS: Gene therapy involves delivery of exogenous DNA to provide a therapeutic protein. Ideally, a gene therapy vector should be non-toxic, non-immunogenic, easy to produce, and efficient in protecting and delivering DNA into target cells. METHODS: Adeno-associated virus (AAV) offers thes...

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Detalles Bibliográficos
Autores principales:	Chung, Daniel C., Fogelgren, Ben, Park, Kwon Moo, Heidenberg, Jessica, Zuo, Xiaofeng, Huang, Liwei, Bennett, Jean, Lipschutz, Joshua H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	S. Karger AG 2011
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290852/ https://www.ncbi.nlm.nih.gov/pubmed/22470395 http://dx.doi.org/10.1159/000333071

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