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Aquaporin-2 Promoter Is Synergistically Regulated by Nitric Oxide and Nuclear Factor of Activated T Cells

BACKGROUND/AIMS: We have previously shown that aquaporin-2 (AQP2) is down-regulated in the renal medulla of rats made hypertensive by chronic inhibition of nitric oxide synthase. It has been shown that AQP2 expression is regulated by the calcineurin/nuclear factor of activated T cells (NFATc). Nitri...

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Detalles Bibliográficos
Autores principales: Albertoni Borghese, María F., Bettini, Layne M., Nitta, Carlos H., de Frutos, Sergio, Majowicz, Mónica, Gonzalez Bosc, Laura V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290856/
https://www.ncbi.nlm.nih.gov/pubmed/22470386
http://dx.doi.org/10.1159/000333066