Crosstalk between Smad and Mitogen-Activated Protein Kinases for the Regulation of Apoptosis in Cyclosporine A- Induced Renal Tubular Injury

BACKGROUND/AIMS: It remains elusive whether there is a crosstalk between Smad and mitogen-activated protein kinases (MAPKs) and whether it regulates cyclosporine A (CyA)-induced apoptosis in renal proximal tubular cells (RPTCs). METHODS: The effect of CyA on nuclear translocation of Smad2/3 and MAPK...

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Detalles Bibliográficos
Autores principales: Iwayama, Hideyuki, Sakamoto, Tatsuo, Nawa, Akihiro, Ueda, Norishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2011
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290860/
https://www.ncbi.nlm.nih.gov/pubmed/22470391
http://dx.doi.org/10.1159/000333014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290860/
https://www.ncbi.nlm.nih.gov/pubmed/22470391
http://dx.doi.org/10.1159/000333014

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