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Crosstalk between Smad and Mitogen-Activated Protein Kinases for the Regulation of Apoptosis in Cyclosporine A- Induced Renal Tubular Injury

BACKGROUND/AIMS: It remains elusive whether there is a crosstalk between Smad and mitogen-activated protein kinases (MAPKs) and whether it regulates cyclosporine A (CyA)-induced apoptosis in renal proximal tubular cells (RPTCs). METHODS: The effect of CyA on nuclear translocation of Smad2/3 and MAPK...

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Detalles Bibliográficos
Autores principales:	Iwayama, Hideyuki, Sakamoto, Tatsuo, Nawa, Akihiro, Ueda, Norishi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	S. Karger AG 2011
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290860/ https://www.ncbi.nlm.nih.gov/pubmed/22470391 http://dx.doi.org/10.1159/000333014

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