The amino-acid mutational spectrum of human genetic disease

BACKGROUND: Nonsynonymous mutations in the coding regions of human genes are responsible for phenotypic differences between humans and for susceptibility to genetic disease. Computational methods were recently used to predict deleterious effects of nonsynonymous human mutations and polymorphisms. He...

Descripción completa

Detalles Bibliográficos
Autores principales: Vitkup, Dennis, Sander, Chris, Church, George M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC329120/
https://www.ncbi.nlm.nih.gov/pubmed/14611658
http://dx.doi.org/10.1186/gb-2003-4-11-r72

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC329120/
https://www.ncbi.nlm.nih.gov/pubmed/14611658
http://dx.doi.org/10.1186/gb-2003-4-11-r72

Ejemplares similares