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The amino-acid mutational spectrum of human genetic disease
BACKGROUND: Nonsynonymous mutations in the coding regions of human genes are responsible for phenotypic differences between humans and for susceptibility to genetic disease. Computational methods were recently used to predict deleterious effects of nonsynonymous human mutations and polymorphisms. He...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2003
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC329120/ https://www.ncbi.nlm.nih.gov/pubmed/14611658 http://dx.doi.org/10.1186/gb-2003-4-11-r72 |