Insulin/IGF-1 and Hypoxia Signaling Act in Concert to Regulate Iron Homeostasis in Caenorhabditis elegans

Iron plays an essential role in many biological processes, but also catalyzes the formation of reactive oxygen species (ROS), which can cause molecular damage. Iron homeostasis is therefore a critical determinant of fitness. In Caenorhabditis elegans, insulin/IGF-1 signaling (IIS) promotes growth an...

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Detalles Bibliográficos
Autores principales: Ackerman, Daniel, Gems, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291539/
https://www.ncbi.nlm.nih.gov/pubmed/22396654
http://dx.doi.org/10.1371/journal.pgen.1002498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291539/
https://www.ncbi.nlm.nih.gov/pubmed/22396654
http://dx.doi.org/10.1371/journal.pgen.1002498

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