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EBV-Encoded LMP1 Upregulates Igκ 3′Enhancer Activity and Igκ Expression in Nasopharyngeal Cancer Cells by Activating the Ets-1 through ERKs Signaling

Accumulating evidence indicates that epithelial cancer cells, including nasopharyngeal carcinoma (NPC) cells, express immunoglobulins (Igs). We previously found that the expression of the kappa light chain protein in NPC cells can be upregulated by the EBV-encoded latent membrane protein 1 (LMP1). I...

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Detalles Bibliográficos
Autores principales: Liu, Haidan, Duan, Zhi, Zheng, Hui, Hu, Duosha, Li, Ming, Tao, Yongguang, Bode, Ann M., Dong, Zigang, Cao, Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291551/
https://www.ncbi.nlm.nih.gov/pubmed/22396784
http://dx.doi.org/10.1371/journal.pone.0032624