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Critical Role of Perforin-dependent CD8+ T Cell Immunity for Rapid Protective Vaccination in a Murine Model for Human Smallpox

Vaccination is highly effective in preventing various infectious diseases, whereas the constant threat of new emerging pathogens necessitates the development of innovative vaccination principles that also confer rapid protection in a case of emergency. Although increasing evidence points to T cell i...

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Detalles Bibliográficos
Autores principales: Kremer, Melanie, Suezer, Yasemin, Volz, Asisa, Frenz, Theresa, Majzoub, Monir, Hanschmann, Kay-Martin, Lehmann, Michael H., Kalinke, Ulrich, Sutter, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291617/
https://www.ncbi.nlm.nih.gov/pubmed/22396645
http://dx.doi.org/10.1371/journal.ppat.1002557