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Critical Role of Perforin-dependent CD8+ T Cell Immunity for Rapid Protective Vaccination in a Murine Model for Human Smallpox
Vaccination is highly effective in preventing various infectious diseases, whereas the constant threat of new emerging pathogens necessitates the development of innovative vaccination principles that also confer rapid protection in a case of emergency. Although increasing evidence points to T cell i...
Autores principales: | Kremer, Melanie, Suezer, Yasemin, Volz, Asisa, Frenz, Theresa, Majzoub, Monir, Hanschmann, Kay-Martin, Lehmann, Michael H., Kalinke, Ulrich, Sutter, Gerd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291617/ https://www.ncbi.nlm.nih.gov/pubmed/22396645 http://dx.doi.org/10.1371/journal.ppat.1002557 |
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