Mutation of zebrafish dihydrolipoamide branched-chain transacylase E2 results in motor dysfunction and models maple syrup urine disease

Analysis of zebrafish mutants that demonstrate abnormal locomotive behavior can elucidate the molecular requirements for neural network function and provide new models of human disease. Here, we show that zebrafish quetschkommode (que) mutant larvae exhibit a progressive locomotor defect that culmin...

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Detalles Bibliográficos
Autores principales: Friedrich, Timo, Lambert, Aaron M., Masino, Mark A., Downes, Gerald B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291646/
https://www.ncbi.nlm.nih.gov/pubmed/22046030
http://dx.doi.org/10.1242/dmm.008383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291646/
https://www.ncbi.nlm.nih.gov/pubmed/22046030
http://dx.doi.org/10.1242/dmm.008383

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