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Modeling and Simulation of Aggregation of Membrane Protein LAT with Molecular Variability in the Number of Binding Sites for Cytosolic Grb2-SOS1-Grb2

The linker for activation of T cells (LAT), the linker for activation of B cells (LAB), and the linker for activation of X cells (LAX) form a family of transmembrane adaptor proteins widely expressed in lymphocytes. These scaffolding proteins have multiple binding motifs that, when phosphorylated, b...

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Detalles Bibliográficos
Autores principales: Nag, Ambarish, Monine, Michael, Perelson, Alan S., Goldstein, Byron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291652/
https://www.ncbi.nlm.nih.gov/pubmed/22396725
http://dx.doi.org/10.1371/journal.pone.0028758