CD36-mediated activation of endothelial cell apoptosis by an N-terminal recombinant fragment of thrombospondin-2 inhibits breast cancer growth and metastasis in vivo

Thus far the clinical benefits seen in breast cancer patients treated with drugs targeting the vascular endothelial growth factor (VEGF) pathway are only modest. Consequently, additional antiangiogenic approaches for treatment of breast cancer need to be investigated. Thrombospondin-2 (TSP-2) has be...

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Detalles Bibliográficos
Autores principales: Koch, Manuel, Hussein, Fadi, Woeste, Andreas, Gründker, Carsten, Frontzek, Karl, Emons, Günter, Hawighorst, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Preclinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291836/
https://www.ncbi.nlm.nih.gov/pubmed/20714802
http://dx.doi.org/10.1007/s10549-010-1085-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291836/
https://www.ncbi.nlm.nih.gov/pubmed/20714802
http://dx.doi.org/10.1007/s10549-010-1085-7

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