TNF-α and TGF-β Counter-Regulate PD-L1 Expression on Monocytes in Systemic Lupus Erythematosus

Monocytes in patients with systemic lupus erythematosus (SLE) are hyperstimulatory for T lymphocytes. We previously found that the normal program for expression of a negative costimulatory molecule programmed death ligand-1 (PD-L1) is defective in SLE patients with active disease. Here, we investiga...

Descripción completa

Detalles Bibliográficos
Autores principales: Ou, Jing-Ni, Wiedeman, Alice E., Stevens, Anne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291882/
https://www.ncbi.nlm.nih.gov/pubmed/22389764
http://dx.doi.org/10.1038/srep00295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291882/
https://www.ncbi.nlm.nih.gov/pubmed/22389764
http://dx.doi.org/10.1038/srep00295

Ejemplares similares