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Nanoscopic and Photonic Ultrastructural Characterization of Two Distinct Insulin Amyloid States

Two different conformational isoforms or amyloid strains of insulin with different cytotoxic capacity have been described previously. Herein these filamentous and fibrillar amyloid states of insulin were investigated using biophysical and spectroscopic techniques in combination with luminescent conj...

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Detalles Bibliográficos
Autores principales: Psonka-Antonczyk, Katarzyna Maria, Duboisset, Julien, Stokke, Bjørn Torger, Zako, Tamotsu, Kobayashi, Takahiro, Maeda, Mizuo, Nyström, Sofie, Mason, Jeff, Hammarström, Per, Nilsson, K. Peter R., Lindgren, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291971/
https://www.ncbi.nlm.nih.gov/pubmed/22408402
http://dx.doi.org/10.3390/ijms13021461