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ACVR1, a Therapeutic Target of Fibrodysplasia Ossificans Progressiva, Is Negatively Regulated by miR-148a

Fibrodysplasia ossificans progressiva (FOP) is a rare congenital disorder of skeletal malformations and progressive extraskeletal ossification. There is still no effective treatment for FOP. All FOP individuals harbor conserved point mutations in ACVR1 gene that are thought to cause ACVR1 constituti...

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Detalles Bibliográficos
Autores principales: Song, Hao, Wang, Qi, Wen, Junge, Liu, Shunai, Gao, Xuesong, Cheng, Jun, Zhang, Deli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292007/
https://www.ncbi.nlm.nih.gov/pubmed/22408438
http://dx.doi.org/10.3390/ijms13022063