Ubiquitin-dependent regulation of COPII coat size and function

Packaging of proteins from the ER into COPII-vesicles is essential for secretion. In cells, most COPII-vesicles are ~60-80nm in diameter, yet some must increase their size to accommodate 300-400nm procollagen fibers or chylomicrons. Impaired COPII function results in collagen deposition defects, cra...

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Detalles Bibliográficos
Autores principales: Jin, Lingyan, Pahuja, Kanika Bajaj, Wickliffe, Katherine E., Gorur, Amita, Baumgärtel, Christine, Schekman, Randy, Rape, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292188/
https://www.ncbi.nlm.nih.gov/pubmed/22358839
http://dx.doi.org/10.1038/nature10822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292188/
https://www.ncbi.nlm.nih.gov/pubmed/22358839
http://dx.doi.org/10.1038/nature10822

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