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Proteomic Plasma Membrane Profiling Reveals an Essential Role for gp96 in the Cell Surface Expression of LDLR Family Members, Including the LDL Receptor and LRP6

[Image: see text] The endoplasmic reticulum chaperone gp96 is required for the cell surface expression of a narrow range of proteins, including toll-like receptors (TLRs) and integrins. To identify a more comprehensive repertoire of proteins whose cell surface expression is dependent on gp96, we dev...

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Detalles Bibliográficos
Autores principales: Weekes, Michael P., Antrobus, Robin, Talbot, Suzanne, Hör, Simon, Simecek, Nikol, Smith, Duncan L., Bloor, Stuart, Randow, Felix, Lehner, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292266/
https://www.ncbi.nlm.nih.gov/pubmed/22292497
http://dx.doi.org/10.1021/pr201135e