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Cardiomyocyte overexpression of miR-27b induces cardiac hypertrophy and dysfunction in mice

Recent studies have begun to reveal critical roles of microRNAs (miRNAs) in the pathogenesis of cardiac hypertrophy and dysfunction. In this study, we tested whether a transforming growth factor-β (TGF-β)-regulated miRNA played a pivotal role in the development of cardiac hypertrophy and heart failu...

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Detalles Bibliográficos
Autores principales: Wang, Jian, Song, Yao, Zhang, Yan, Xiao, Han, Sun, Qiang, Hou, Ning, Guo, Shuilong, Wang, Youliang, Fan, Kaiji, Zhan, Dawei, Zha, Lagabaiyila, Cao, Yang, Li, Zhenhua, Cheng, Xuan, Zhang, Youyi, Yang, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292295/
https://www.ncbi.nlm.nih.gov/pubmed/21844895
http://dx.doi.org/10.1038/cr.2011.132