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Recombinant Human Leptin Treatment Does Not Improve Insulin Action in Obese Subjects With Type 2 Diabetes

OBJECTIVE: Leptin therapy improves insulin sensitivity in people with leptin deficiency, but it is not known whether it improves insulin action in people who are not leptin deficient. The purpose of the current study was to determine whether leptin treatment has weight loss–independent effects on in...

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Detalles Bibliográficos
Autores principales: Mittendorfer, Bettina, Horowitz, Jeffrey F., DePaoli, Alex M., McCamish, Mark A., Patterson, Bruce W., Klein, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292320/
https://www.ncbi.nlm.nih.gov/pubmed/21411512
http://dx.doi.org/10.2337/db10-1302