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Rapid Tachyphylaxis of the Glucagon-Like Peptide 1–Induced Deceleration of Gastric Emptying in Humans

OBJECTIVE: Glucagon-like peptide (GLP)-1 lowers postprandial glycemia primarily through inhibition of gastric emptying. We addressed whether the GLP-1–induced deceleration of gastric emptying is subject to rapid tachyphylaxis and if so, how this would alter postprandial glucose control. RESEARCH DES...

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Detalles Bibliográficos
Autores principales: Nauck, Michael A., Kemmeries, Guido, Holst, Jens J., Meier, Juris J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292331/
https://www.ncbi.nlm.nih.gov/pubmed/21430088
http://dx.doi.org/10.2337/db10-0474