Genetic Ablation of cGMP-Dependent Protein Kinase Type I Causes Liver Inflammation and Fasting Hyperglycemia

OBJECTIVE: The nitric oxide/cGMP/cGMP-dependent protein kinase type I (cGKI) signaling pathway regulates cell functions that play a pivotal role in the pathogenesis of type 2 diabetes. However, the impact of a dysfunction of this pathway for glucose metabolism in vivo is unknown. RESEARCH DESIGN AND...

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Detalles Bibliográficos
Autores principales: Lutz, Stefan Z., Hennige, Anita M., Feil, Susanne, Peter, Andreas, Gerling, Andrea, Machann, Jürgen, Kröber, Stefan M., Rath, Michaela, Schürmann, Annette, Weigert, Cora, Häring, Hans-Ulrich, Feil, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Pathophysiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292332/
https://www.ncbi.nlm.nih.gov/pubmed/21464444
http://dx.doi.org/10.2337/db10-0760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292332/
https://www.ncbi.nlm.nih.gov/pubmed/21464444
http://dx.doi.org/10.2337/db10-0760

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