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FTO, Type 2 Diabetes, and Weight Gain Throughout Adult Life: A Meta-Analysis of 41,504 Subjects From the Scandinavian HUNT, MDC, and MPP Studies

OBJECTIVE: FTO is the most important polygene identified for obesity. We aimed to investigate whether a variant in FTO affects type 2 diabetes risk entirely through its effect on BMI and how FTO influences BMI across adult life span. RESEARCH DESIGN AND METHODS: Through regression models, we assesse...

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Detalles Bibliográficos
Autores principales: Hertel, Jens K., Johansson, Stefan, Sonestedt, Emily, Jonsson, Anna, Lie, Rolv T., Platou, Carl G.P., Nilsson, Peter M., Rukh, Gull, Midthjell, Kristian, Hveem, Kristian, Melander, Olle, Groop, Leif, Lyssenko, Valeriya, Molven, Anders, Orho-Melander, Marju, Njølstad, Pål R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292341/
https://www.ncbi.nlm.nih.gov/pubmed/21398525
http://dx.doi.org/10.2337/db10-1340