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Lipid-bound apolipoproteins in tyrosyl radical-oxidized HDL stabilize ABCA1 like lipid-free apolipoprotein A-I

BACKGROUND: ATP-binding cassette transporter A1 (ABCA1) mediates the lipidation of exchangeable apolipoproteins, the rate-limiting step in the formation of high density lipoproteins (HDL). We previously demonstrated that HDL oxidized ex vivo by peroxidase-generated tyrosyl radical (tyrosylated HDL,...

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Detalles Bibliográficos
Autores principales: Hossain, Mohammad A, Ngeth, Sereyrath, Chan, Teddy, Oda, Michael N, Francis, Gordon A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292454/
https://www.ncbi.nlm.nih.gov/pubmed/22248050
http://dx.doi.org/10.1186/1471-2091-13-1