TDT-HET: A new transmission disequilibrium test that incorporates locus heterogeneity into the analysis of family-based association data

BACKGROUND: Locus heterogeneity is one of the most documented phenomena in genetics. To date, relatively little work had been done on the development of methods to address locus heterogeneity in genetic association analysis. Motivated by Zhou and Pan's work, we present a mixture model of linked...

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Detalles Bibliográficos
Autores principales: Londono, Douglas, Buyske, Steven, Finch, Stephen J, Sharma, Swarkar, Wise, Carol A, Gordon, Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292499/
https://www.ncbi.nlm.nih.gov/pubmed/22264315
http://dx.doi.org/10.1186/1471-2105-13-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292499/
https://www.ncbi.nlm.nih.gov/pubmed/22264315
http://dx.doi.org/10.1186/1471-2105-13-13

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