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TDT-HET: A new transmission disequilibrium test that incorporates locus heterogeneity into the analysis of family-based association data
BACKGROUND: Locus heterogeneity is one of the most documented phenomena in genetics. To date, relatively little work had been done on the development of methods to address locus heterogeneity in genetic association analysis. Motivated by Zhou and Pan's work, we present a mixture model of linked...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292499/ https://www.ncbi.nlm.nih.gov/pubmed/22264315 http://dx.doi.org/10.1186/1471-2105-13-13 |